Our research focuses on vascular ion channels and signal transduction pathways. To investigate how they impact blood flow control, we use different imaging techniques, electrophysiology and genetically-engineered mouse models.

Our investigations span the full spectrum from the single molecule level to the whole in vivo level. The major goal of our research is to understand vascular signaling, blood flow control and the changes associated with small vessel and neurodegenerative diseases as well as aging.

Key Research Areas:

  • Ion channels and Biophysics

  • Neurovascular coupling and Cerebral blood flow regulation

  • Vascular mechanical interoception

  • Small vessel and neurodegenerative diseases

Selected Published Work:

Support for Ongoing Research:

  • R01 (NIH-NHLBI)

  • R21 (NIH-NIA)

  • P20 (NIH-NIGMS)

  • Bloomfield Professorship in Cardiovascular Research

  • Chan Zuckerberg Initiative Neurodegeneration