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Our research focuses on vascular ion channels and signal transduction pathways. To investigate how they impact blood flow control, we use different imaging techniques, electrophysiology and genetically-engineered mouse models.
Our investigations span the full spectrum from the single molecule level to the whole in vivo level. The major goal of our research is to understand vascular signaling, blood flow control and the changes associated with small vessel and neurodegenerative diseases as well as aging.
Key Research Areas:
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Ion channels and Biophysics
Neurovascular coupling and Cerebral blood flow regulation
Vascular mechanical interoception
Small vessel and neurodegenerative diseases
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Selected Published Work:
Lim, Abd Alhaseeb...Harraz, Nature Communications 2024
Lim, Willemse, Harraz, Biophysical J 2025
Harraz et al., Circulation Research 2022
Harraz, Delpire, Physiol Rev 2024
Grandi et al., J Physiol 2023
Harraz et al., PNAS 2018
Harraz, Function 2023
Harraz et al., eLife 2018
Dabertrand*, Harraz* et al., PNAS 2021
Mughal*, Harraz* et al., Function 2021
Support for Ongoing Research:
R01 (NIH-NHLBI)
R21 (NIH-NIA)
P20 (NIH-NIGMS)
Bloomfield Professorship in Cardiovascular Research
Chan Zuckerberg Initiative Neurodegeneration